Pregnancy
According to the California Environmental Protection Agency, clobetasol propionate should not be used by pregnant women, or women expecting to become pregnant soon, as studies with rats shows a risk of birth defects:
"Studies in the rat following oral administration at dosage levels up to 50 mg/kg per day revealed that the females exhibited an increase in the number of resorbed embryos and a decrease in the number of living fetuses at the highest dose. Pregnancy: Teratogenic Effects (i.e., possibility of causing abnormalities in fetuses): Pregnancy Category C: Clobetasol propionate has not been tested for teratogenicity when applied topically; however, it is absorbed percutaneously, and when administered subcutaneously it was a significant teratogen in both the rabbit and mouse. Clobetasol propionate has greater teratogenic potential than steroids that are less potent.There are no adequate and well-controlled studies of the teratogenic effects of clobetasol propionate in pregnant women. Temovate Cream and Ointment should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus."
Read more about this topic: Clobetasol Propionate
Famous quotes containing the word pregnancy:
“Back in the days when men were hunters and chestbeaters and women spent their whole lives worrying about pregnancy or dying in childbirth, they often had to be taken against their will. Men complained that women were cold, unresponsive, frigid.... They wanted their women wanton. They wanted their women wild. Now women were finally learning to be wanton and wild—and what happened? The men wilted.”
—Erica Jong (b. 1942)
“It is now quite lawful for a Catholic woman to avoid pregnancy by a resort to mathematics, though she is still forbidden to resort to physics and chemistry.”
—H.L. (Henry Lewis)
“There are highly gifted spirits who are always infertile simply because, owing to a weakness in temperament, they are too impatient to wait out their pregnancy to term.”
—Friedrich Nietzsche (1844–1900)