Cleft Lip and Palate - Epidemiology

Epidemiology

Prevalence rates reported for live births for Cleft lip with or without Cleft Palate (CL ± P) and Cleft Palate alone (CPO) varies within different ethnic groups.

The highest prevalence rates for (CL ± P) are reported for Native Americans and Asians. Africans have the lowest prevalence rates.

  • Native Americans: 3.74/1000
  • Japanese: 0.82/1000 to 3.36/1000
  • Chinese: 1.45/1000 to 4.04/1000
  • Caucasians: 1.43/1000 to 1.86/1000
  • Latin Americans: 1.04/1000
  • Africans: 0.18/1000 to 1.67/1000

Rate of occurrence of CPO is similar for Caucasians, Africans, North American natives, Japanese and Chinese. The trait is dominant.

Prevalence of "cleft uvula" has varied from .02% to 18.8% with the highest numbers found among Chippewa and Navajo and the lowest generally in Africans.

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