Classical genetics consists of the technique and methodologies of genetics that predate the advent of molecular biology. A key discovery of classical genetics in eukaryotes was genetic linkage. The observation that some genes do not segregate independently at meiosis broke the laws of Mendelian inheritance, and provided science with a way to map characteristics to a location on the chromosomes. Linkage maps are still used today, especially in breeding for plant improvement.
After the discovery of the genetic code and such tools of cloning as restriction enzymes, the avenues of investigation open to geneticists were greatly broadened. Some classical genetic ideas have been supplanted with the mechanistic understanding brought by molecular discoveries, but many remain intact and in use. Classical genetics is often contrasted with reverse genetics, and aspects of molecular biology are sometimes referred to as molecular genetics.
Other articles related to "classical genetics, classical, genetics, genetic":
... By the classical genetics approach, a researcher would then locate (map) the gene on its chromosome by crossbreeding with individuals that carry other unusual traits and ... Classical geneticists would have used phenotypic traits to map the new mutant alleles ... This type of saturation mutagenesis within classical experiments was used to define sets of genes that were a bare minimum for the appearance of specific phenotypes ...
... chromosome theory 1905 William Bateson coins the term "genetics" in a letter to Adam Sedgwick and at a meeting in 1908 ... Hardy-Weinberg law derived ... reside on chromosomes 1913 Alfred Sturtevant makes the first genetic map of a chromosome 1913 Gene maps show chromosomes containing linear arranged ... See population genetics ...
Famous quotes containing the word classical:
“Culture is a sham if it is only a sort of Gothic front put on an iron buildinglike Tower Bridgeor a classical front put on a steel framelike the Daily Telegraph building in Fleet Street. Culture, if it is to be a real thing and a holy thing, must be the product of what we actually do for a livingnot something added, like sugar on a pill.”
—Eric Gill (18821940)