Ciliopathy - Clinical Symptoms and Ciliary Roles

Clinical Symptoms and Ciliary Roles

A wide variety of symptoms are potential clinical features of ciliopathy.

  • Chemosensation abnormalities, typically via ciliated epithelial cellular dysfunction.
  • Defective thermosensation or mechanosensation, often via ciliated epithelial cellular dysfunction.
  • Cellular motility dysfunction
  • Issues with displacement of extracellular fluid
  • Paracrine signal transduction abnormalities

In organisms of normal health, cilia are critical for:

  • organism development
  • homeostasis
  • reproduction

Read more about this topic:  Ciliopathy

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