Diagnosis
Diagnostic techniques:
- antibodies (IgG) precipitates complement (C3) in the lamina lucida of the basement membrane.
- Circulating auto-antibodies to BP-1 antigen (located in hemidesmosome). 50% have BP-2.
- Negative Nikolsky sign.
- IgG, C3 deposition at BM creating smooth line in immunofluorescent analysis.
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