Chronic Somogyi rebound, also called the Somogyi effect and posthypoglycemic hyperglycemia, is a rebounding high blood sugar that is a response to low blood sugar. When managing the blood glucose level with insulin injections, this effect is counter-intuitive to insulin users who experience high blood sugar in the morning as a result of an overabundance of insulin at night.
This theoretical phenomenon was named after Dr. Michael Somogyi, a Hungarian-born professor of biochemistry at the Washington University and Jewish Hospital of St. Louis, who prepared the first insulin treatment given to a child with diabetes in the USA in October 1922. Somogyi showed that excessive insulin makes diabetes unstable and first published his findings in 1938.
Compare with the dawn phenomenon, which is a morning rise in blood sugar in response to waning insulin and a growth hormone surge (that further antagonizes insulin).
Read more about Chronic Somogyi Rebound: Background, Detection, Avoidance, Controversy
Famous quotes containing the words chronic and/or rebound:
“What the horrors of war are, no one can imagine. They are not wounds and blood and fever, spotted and low, or dysentery, chronic and acute, cold and heat and famine. They are intoxication, drunken brutality, demoralisation and disorder on the part of the inferior ... jealousies, meanness, indifference, selfish brutality on the part of the superior.”
—Florence Nightingale (1820–1910)
“It is odd but agitation or contest of any kind gives a rebound to my spirits and sets me up for a time.”
—George Gordon Noel Byron (1788–1824)