Chronic Endothelial Injury Hypothesis - Origins of The Hypothesis

Origins of The Hypothesis

Ross and Glomset initially proposed that endothelial cell uncovering was the first step in the development of atherosclerosis. Other hypotheses have associated the role of infectious agents (e.g. cytomegalovirus, Chlamydia pneumoniae and Helicobacter pylori) in inflammatory responses in the arterial wall. Currently, most research seems to focus on inflammatory processes which associate endothelial dysfunction with lipoprotein accumulation.

Read more about this topic:  Chronic Endothelial Injury Hypothesis

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    Grown onto every inch of plate, except
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    Grown onto every inch of plate, except
    Where the hinges let it move, were living things,
    Barnacles, mussels, water weeds—and one
    Blue bit of polished glass, glued there by time:
    The origins of art.
    Howard Moss (b. 1922)

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