Precautions
Water insoluble chromium(III) compounds and chromium metal are not considered a health hazard, while the toxicity and carcinogenic properties of chromium(VI) have been known for a long time. Because of the specific transport mechanisms, only limited amounts of chromium(III) enter the cells. Several in vitro studies indicated that high concentrations of chromium(III) in the cell can lead to DNA damage. Acute oral toxicity ranges between 1.5 and 3.3 mg/kg. The proposed beneficial effects of chromium(III) and the use as dietary supplements yielded some controversial results, but recent reviews suggest that moderate uptake of chromium(III) through dietary supplements poses no risk.
Read more about this topic: Chromium Compounds
Famous quotes containing the word precautions:
“We must take precautions against being prematurely honed sharp—since at the same time we are being prematurely honed thin.”
—Friedrich Nietzsche (1844–1900)
“A multitude of little superfluous precautions engender here a population of deputies and sub-officials, each of whom acquits himself with an air of importance and a rigorous precision, which seemed to say, though everything is done with much silence, “Make way, I am one of the members of the grand machine of state.””
—Marquis De Custine (1790–1857)
“It is so manifestly incompatible with those precautions for our peace and safety, which all the great powers habitually observe and enforce in matters affecting them, that a shorter water way between our eastern and western seaboards should be dominated by any European government, that we may confidently expect that such a purpose will not be entertained by any friendly power.”
—Benjamin Harrison (1833–1901)