Computing
- Google Chrome, a web browser
- Google Chrome OS, a web-centric Linux-based operating system
- Chrome (programming language) or Oxygene, an Object Pascal implementation for the .NET Framework
- User interface chrome, the borders and widgets that frame the content part of a window
- Chrome Mozilla or XUL, the Mozilla XML user interface language
- S3 Chrome, a series of graphics accelerators
- Microsoft Chrome, an API for DirectX
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