Issue
- Cosimo II de' Medici, Grand Duke of Tuscany (1590–1621) married Maria Maddalena of Austria and had issue.
- Eleonora de' Medici (1591–1617) died unmarried.
- Caterina de' Medici (1593–1629) married Ferdinando Gonzaga, Duke of Mantua, later Governor of Siena;
- Francesco de' Medici (1594–1614) died unmarried.
- Carlo de' Medici (1595–1666) died unmarried.
- Filippino de' Medici (1598–1602) died unmarried.
- Lorenzo de' Medici (1599–1648) died unmarried.
- Maria Maddalena de' Medici (1600–1633) died unmarried.
- Claudia de' Medici (1604–1648) married (1) Federico della Rovere and had issue (2) Leopold V, Archduke of Austria and had issue.
Read more about this topic: Christina Of Lorraine
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