Chlamydia Trachomatis - Laboratory Tests

Laboratory Tests

  • Nucleic acid amplification tests (NAAT). These tests find the genetic material (DNA) of chlamydia bacteria. These tests are the most sensitive tests available. That means they are very accurate and that they are very unlikely to have false-negative test results. A polymerase chain reaction (PCR) test is an example of a nucleic acid amplification test. This test can also be done on a urine sample.
  • Nucleic acid hybridization tests (DNA probe test). A probe test also finds chlamydia DNA. A probe test is very accurate but is not as sensitive as nucleic acid amplification tests.
  • Enzyme-linked immunosorbent assay (ELISA, EIA). This quick test finds substances (chlamydia antigens) that trigger the immune system to fight chlamydia infection.
  • Direct fluorescent antibody test (DFA). This quick test also finds chlamydia antigens.
  • Chlamydia culture. A culture is a special cup that allows the chlamydia bacteria to grow. This test is more expensive, and the results take longer (5 to 7 days) than the other tests. The culture must be done in a lab.

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