Children's Oncology Group - Spectrum of COG Research

Spectrum of COG Research

COG’s research studies encompass hematologic malignancies, solid tumors, central nervous system tumors, and rare cancers. Hematologic malignancies include the most common childhood cancer, acute lymphoblastic leukemia, as well as acute myeloid leukemia, non-Hodgkin lymphoma, and Hodgkin lymphoma. Pediatric solid tumors studied include neuroblastoma, tumors of bone (Ewing sarcoma, osteosarcoma), tumors of the kidney (Wilms' tumor), rhabdomyosarcoma and other soft tissue sarcomas. Central nervous system (brain) tumors are the second most common form of childhood cancer. COG conducts research in children with medulloblastoma, ependymoma, brainstem gliomas, low and high-grade gliomas, and germ cell tumors. The large multi-site structure of COG also allows it to conduct research into very rare childhood cancer including retinoblastoma, hepatoblastoma, and other tumors.

In addition to disease specific research, COG conducts studies in developmental therapeutics (new cancer drug development), supportive care, epidemiology, stem cell transplantation, behavioral sciences and survivorship.

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