CHI3L1 - Regulation and Mechanism

Regulation and Mechanism

YKL-40 has been linked to activation of the AKT pro-survival (anti-apoptotic) signaling pathway.

YKL-40 is a migration factor for primary astrocytes and its expression is controlled by NFI-X3, STAT3, and AP-1.

Read more about this topic:  CHI3L1

Famous quotes containing the words regulation and/or mechanism:

    Nothing can be more real, or concern us more, than our own sentiments of pleasure and uneasiness; and if these be favourable to virtue and unfavourable to vice, no more can be requisite to the regulation of our conduct and behavior.
    David Hume (1711–1776)

    When one of us dies of cancer, loses her mind, or commits suicide, we must not blame her for her inability to survive an ongoing political mechanism bent on the destruction of that human being. Sanity remains defined simply by the ability to cope with insane conditions.
    Ana Castillo (b. 1953)