Chemokine - Types

Types

CC chemokines
Name Gene Other name(s) Receptor Uniprot
CCL1 Scya1 I-309, TCA-3 CCR8
CCL2 Scya2 MCP-1 CCR2 P13500
CCL3 Scya3 MIP-1a CCR1 P10147
CCL4 Scya4 MIP-1β CCR1, CCR5 P13236
CCL5 Scya5 RANTES CCR5 P13501
CCL6 Scya6 C10, MRP-2 CCR1 P27784
CCL7 Scya7 MARC, MCP-3 CCR2 P80098
CCL8 Scya8 MCP-2 CCR1, CCR2B, CCR5 P80075
CCL9/CCL10 Scya9 MRP-2, CCF18, MIP-1? CCR1 P51670
CCL11 Scya11 Eotaxin CCR2, CCR3, CCR5 P51671
CCL12 Scya12 MCP-5 Q62401
CCL13 Scya13 MCP-4, NCC-1, Ckβ10 CCR2, CCR3, CCR5 Q99616
CCL14 Scya14 HCC-1, MCIF, Ckβ1, NCC-2, CCL CCR1 Q16627
CCL15 Scya15 Leukotactin-1, MIP-5, HCC-2, NCC-3 CCR1, CCR3 Q16663
CCL16 Scya16 LEC, NCC-4, LMC, Ckβ12 CCR1, CCR2, CCR5, CCR8 O15467
CCL17 Scya17 TARC, dendrokine, ABCD-2 CCR4 Q92583
CCL18 Scya18 PARC, DC-CK1, AMAC-1, Ckβ7, MIP-4 P55774
CCL19 Scya19 ELC, Exodus-3, Ckβ11 CCR7 Q99731
CCL20 Scya20 LARC, Exodus-1, Ckβ4 CCR6 P78556
CCL21 Scya21 SLC, 6Ckine, Exodus-2, Ckβ9, TCA-4 CCR7 O00585
CCL22 Scya22 MDC, DC/β-CK CCR4 O00626
CCL23 Scya23 MPIF-1, Ckβ8, MIP-3, MPIF-1 CCR1 P55773
CCL24 Scya24 Eotaxin-2, MPIF-2, Ckβ6 CCR3 O00175
CCL25 Scya25 TECK, Ckβ15 CCR9 O15444
CCL26 Scya26 Eotaxin-3, MIP-4a, IMAC, TSC-1 CCR3 Q9Y258
CCL27 Scya27 CTACK, ILC, Eskine, PESKY, skinkine CCR10 Q9Y4X3
CCL28 Scya28 MEC CCR3, CCR10 Q9NRJ3
CXC chemokines
Name Gene Other name(s) Receptor Uniprot
CXCL1 Scyb1 Gro-a, GRO1, NAP-3, KC CXCR2 P09341
CXCL2 Scyb2 Gro-β, GRO2, MIP-2a CXCR2 P19875
CXCL3 Scyb3 Gro-?, GRO3, MIP-2β CXCR2 P19876
CXCL4 Scyb4 PF-4 CXCR3B P02776
CXCL5 Scyb5 ENA-78 CXCR2 P42830
CXCL6 Scyb6 GCP-2 CXCR1, CXCR2 P80162
CXCL7 Scyb7 NAP-2, CTAPIII, β-Ta, PEP P02775
CXCL8 Scyb8 IL-8, NAP-1, MDNCF, GCP-1 CXCR1, CXCR2 P10145
CXCL9 Scyb9 MIG, CRG-10 CXCR3 Q07325
CXCL10 Scyb10 IP-10, CRG-2 CXCR3 P02778
CXCL11 Scyb11 I-TAC, β-R1, IP-9 CXCR3, CXCR7 O14625
CXCL12 Scyb12 SDF-1, PBSF CXCR4, CXCR7 P48061
CXCL13 Scyb13 BCA-1, BLC CXCR5 O43927
CXCL14 Scyb14 BRAK, bolekine O95715
CXCL15 Scyb15 Lungkine, WECHE Q9WVL7
CXCL16 Scyb16 SRPSOX CXCR6 Q9H2A7
CXCL17 VCC-1 DMC, VCC-1 Q6UXB2
C chemokines
Name Gene Other name(s) Receptor Uniprot
XCL1 Scyc1 Lymphotactin a, SCM-1a, ATAC XCR1 P47992
XCL2 Scyc2 Lymphotactin β, SCM-1β XCR1 Q9UBD3
CX3C chemokines
Name Gene Other name(s) Receptor Uniprot
CX3CL1 Scyd1 Fractalkine, Neurotactin, ABCD-3 CX3CR1 P78423

Members of the chemokine family are divided into four groups depending on the spacing of their first two cysteine residues. Thus the nomenclature for chemokines is, e.g.: CCL1 for the ligand 1 of the CC-family of chemokines, and CCR1 for its respective receptor.

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