Charles Gough may refer to:
- Charles Gough (artist), (1784–1805), artist of the romantic period
- Charles John Stanley Gough, VC (1832–1912), soldier who won the Victoria Cross during the Sepoy mutiny
- Frederick Gough, full name Charles Frederick Howard Gough, (1901–1977), soldier and MP for Horsham
- Charlie Gough, footballer
- Charlie Gough (programmer), one of the creators of Halo
- Charles Goff, criminal