Charcot-Wilbrand Syndrome - Detection Methods - FMRI

FMRI

Functional magnetic resonance imaging or functional MRI (fMRI) is the specific MRI procedure associated with measuring brain activity. It does so by detecting changes in blood flow (hemodynamic response) related to the energy utilization by the brain using a specific blood-oxygen-level-dependant contrast. Recently fMRI has come to the forefront of dream research because it does not require the use of dyes or isotopes and allows for brain blood flow and related activity to be monitored during sleep. Specifically analysis of dreaming patients have revealed increased blood flow/oxygen utilization by network consisting of the pontine tegmentum, thalamus, amygdala, basal ganglia, anterior cingulate and occipital cortex. Specifically in CWS activation of the occipital cortex is of great interest and it can monitored through fMRI and combined with patient dream reporting to isolate dream formation. Additionally during sleep fMRI studies have revealed a significant decrease in the activity of the prefrontal cortex which likely accounts for the decrease in time perception, insight, and remembrance of dreams. This can be analyzed in patients to help better differentiate between global dream loss and a lack of visual remembrance. The specific mechanism for deactivation of the prefrontal cortex is unclear due to the complexity of the acetylcholine activation pathway and its expanse into variety of other cortical areas.

Read more about this topic:  Charcot-Wilbrand Syndrome, Detection Methods