CFD may refer to:
- Science and computing
- Computational fluid dynamics, a branch of fluid dynamics
- Counterfactual definiteness, the ability, quantum mechanics, to consider results of unperformed measurements
- Cfengine Daemon, the process that runs Cfengine
- Common Fill Device, an electronic module used to load cryptographic keys into electronic encryption machines
- Constant fraction discriminator, a signal processing component
- Business
- Contract For Difference, a type of financial derivative, where two parties exchange the difference between opening and closing value of an underlying asset
- Control Flow Diagram, is a diagram to describe the control flow of a business process, process or program
- Cumulative Flow Diagram, an area graph that depicts the quantity of work in a given state
- Firefighting organisations
- Calgary Fire Department, the fire department of Calgary, Alberta
- Charlotte Fire Department, the Fire Department of Charlotte, North Carolina
- Chicago Fire Department, the fire department of Chicago, Illinois
- Other
- Cheyenne Frontier Days, an annual rodeo and celebration held in Cheyenne, Wyoming
- Christie Front Drive, a second wave indie/emo band from Denver, Colorado
- Coulter Field (IATA: CFD), an airport in Bryan, Texas
- Compagnie des chemins de fer départementaux, (Compagnie des chemins de fer départementaux french), French rail vehicle manufacturer producing narrow gauge rail vehicles