Cesario may refer to:
- Cesario (Kiddy Grade), a character in the anime series Kiddy Grade
- Cesario (Viola), a character in the Shakespearean comedy Twelfth Night
- Cesario Azucena (21st century), Filipino lawyer
People with the surname Cesario:
- Enzo Cesario (born 1980), Chilean track and road cyclist
- Jeff Cesario (born 1953), American comedian and writer
- Juliet Cesario (born 1966), American character actress