Centauri may refer to:
- Any of the stars (or star systems), in the constellation Centaurus, including:
- Alpha Centauri, a binary star including the brightest star of Centaurus
- Beta Centauri, the second brightest star of Centaurus, at a much greater distance to the Sun
- Proxima Centauri, the nearest to the Sun of all stars, and close to Alpha Centauri
- Sid Meier's Alpha Centauri, a 1999 computer game
- Centauri Production, a Czech computer games company
- Centauri (Babylon 5), a species, civilization, and related terms, in the US TV series Babylon 5
- Centauri, a character in the US movie The Last Starfighter