CDK5R1

CDK5R1

Identifiers Symbols CDK5R1; CDK5P35; CDK5R; NCK5A; p23; p25; p35; p35nck5a External IDs OMIM: 603460 MGI: 101764 HomoloGene: 31200 ChEMBL: 2783 GeneCards: CDK5R1 Gene

Gene Ontology
Molecular function	• protein kinase activity • cyclin-dependent protein kinase activity • calcium ion binding • protein binding • kinase activity • cyclin-dependent protein kinase 5 activator activity • protein kinase binding • protein serine/threonine kinase activator activity • cadherin binding
Cellular component	• nucleus • cytoplasm • cytosol • plasma membrane • postsynaptic density • membrane • cyclin-dependent protein kinase 5 holoenzyme complex • axon • dendrite • growth cone • neuromuscular junction • neuronal cell body • dendritic spine • contractile fiber • perinuclear region of cytoplasm
Biological process	• regulation of cyclin-dependent protein kinase activity • neuron migration • neuron cell-cell adhesion • G-protein coupled acetylcholine receptor signaling pathway • axon guidance • axonal fasciculation • brain development • cell proliferation • embryo development • peptidyl-serine phosphorylation • peptidyl-threonine phosphorylation • cerebellum development • superior olivary nucleus maturation • hippocampus development • layer formation in cerebral cortex • neuron differentiation • neuron projection development • regulation of actin cytoskeleton organization • serine phosphorylation of STAT3 protein • ionotropic glutamate receptor signaling pathway • positive regulation of neuron apoptotic process • regulation of neuron differentiation • negative regulation of transcription, DNA-dependent • ephrin receptor signaling pathway • regulation of dendritic spine morphogenesis • regulation of microtubule cytoskeleton organization • positive regulation of protein targeting to membrane
Sources: Amigo / QuickGO

RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 8851 12569 Ensembl ENSG00000176749 ENSMUSG00000048895 UniProt Q15078 P61809 RefSeq (mRNA) NM_003885 NM_009871 RefSeq (protein) NP_003876 NP_034001 Location (UCSC) Chr 17:
30.81 – 30.82 Mb Chr 11:
80.48 – 80.48 Mb PubMed search

Cyclin-dependent kinase 5 activator 1 is an enzyme that in humans is encoded by the CDK5R1 gene.