CD79B

Identifiers Symbols CD79B; AGM6; B29; IGB External IDs OMIM: 147245 MGI: 96431 HomoloGene: 521 GeneCards: CD79B Gene

Gene Ontology
Molecular function transmembrane signaling receptor activity
Cellular component nucleus
nucleolus
cytoplasm
Golgi apparatus
plasma membrane
integral to plasma membrane
external side of plasma membrane
B cell receptor complex
Biological process immune response
signal transduction
B cell receptor signaling pathway
Sources: Amigo / QuickGO
RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 974 15985 Ensembl ENSG00000007312 ENSMUSG00000040592 UniProt P40259 P15530 RefSeq (mRNA) NM_000626 NM_008339 RefSeq (protein) NP_000617 NP_032365 Location (UCSC) Chr 17:
62.01 – 62.01 Mb Chr 11:
106.31 – 106.31 Mb PubMed search

CD79b molecule, immunoglobulin-associated beta, also known as CD79B (Cluster of Differentiation 79B), is a human gene.

It is associated with agammaglobulinemia-6.

The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-beta protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described.