Function
The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system.
The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement.
The protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization.
Read more about this topic: CD46
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