CD247

CD247

Identifiers Symbols CD247; CD3-ZETA; CD3H; CD3Q; CD3Z; T3Z; TCRZ External IDs OMIM: 186780 MGI: 88334 HomoloGene: 12818 GeneCards: CD247 Gene

Gene Ontology
Molecular function	• transmembrane signaling receptor activity • protein binding • identical protein binding • protein homodimerization activity
Cellular component	• cytoplasm • plasma membrane • integral to membrane • T cell receptor complex • alpha-beta T cell receptor complex
Biological process	• viral reproduction • virus-host interaction • T cell costimulation • regulation of defense response to virus by virus • regulation of immune response • T cell receptor signaling pathway
Sources: Amigo / QuickGO

RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 919 12503 Ensembl ENSG00000198821 ENSMUSG00000005763 UniProt P20963 P24161 RefSeq (mRNA) NM_000734 NM_001113391 RefSeq (protein) NP_000725 NP_001106862 Location (UCSC) Chr 1:
167.4 – 167.49 Mb Chr 1:
165.79 – 165.88 Mb PubMed search

T-cell surface glycoprotein CD3 zeta chain also known as T-cell receptor T3 zeta chain or CD247 (Cluster of Differentiation 247) is a protein that in humans is encoded by the CD247 gene.