Castleberry may refer to:
- Castleberry, Alabama - a town in Conecuh County, Alabama, United States.
- Castleberry Hill - a neighborhood in central Atlanta, located southwest of the Central Business District.
- Castleberry Independent School District - a public school district based in River Oaks, Texas (USA).
- Castleberry, Florence Jean - better known "Flo", is a fictional character in the movie Alice Doesn't Live Here Anymore
- Castleberry, Bruce - Former Guitarist of Vallejo (band)
- Castleberry's Food Company, an Augusta, GA-based canned food company