Cascadia, a term that derives from the Cascade Range, may refer to:
- Regional
- The Pacific Northwest
- Cascadia (independence movement)
- Places
- Cascadia, Oregon
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- Cascadia State Park in Cascadia
- Cascadia, Washington
- Other
- 1700 Cascadia earthquake
- Cascadia, a former plant genus now included in Saxifraga
- Cascadia Center for Regional Development, a project of the Discovery Institute
- Cascadia Community College
- Cascadia subduction zone
- Cascadia Wildlands
- The Cascadia Cup, a regional rivalry and trophy in Major League Soccer
Cascadian may refer to:
- Cascadian (train), not to be confused with the Amtrak Cascades