Organizations
- Boise Cascade, an American pulp and paper company
- Cascade Bicycle Club, a non-profit organization and advocacy group, Seattle, Washington
- Cascade Brewery, a brewer in Hobart, Tasmania, Australia
- Cascade College, a private college in Portland, Oregon
- Cascade Communications, a manufacturer of communications equipment
- Cascade Investments LLC, a private investments and holding company owned by Bill Gates
- Cascade Lacrosse, a sports manufacturer
- Cascade Collegiate Conference, a sports conference in the western United States
- Open CASCADE, a software development company with head office in France
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