Cantrell is a surname of English and French origin and may refer to:
- Cantrell (Middlesex cricketer)
- Bill Cantrell, Hydroplane Race Boat Driver
- Blu Cantrell, R&B singer
- Cady Cantrell, model
- Charles P. Cantrell, American Medal of Honor recipient
- Jerry Cantrell, guitarist from Alice in Chains
- Lana Cantrell, Australian Pop Singer
- Laura Cantrell, singer and DJ
- Norda Cantrell, another name for the comic character Northwind
- Peter Cantrell, cricketer
- Rob Cantrell, comedian
- Will Cantrell, a character in the movie Dark Command, a thinly veiled reference to William Quantrill