Calthorpe may refer to:
- Calthorpe cars, made in England up to 1928
Places in England:
- Calthorpe Broad, Norfolk
- Calthorpe, Norfolk
- Calthorpe, Oxfordshire
People:
- Anne Calthorpe (died between 1579 and 1582), Countess of Sussex
- David Calthorpe (born 1973), former Australian rules footballer
- Freddie Calthorpe (1892-1935), English cricketer
- Isabella Calthorpe, stage name of Isabella Anstruther-Gough-Calthorpe (born 1980), English actress and model
- James Calthorpe (1699-1784), English politician and courtier
- Peter Calthorpe, architect and urban designer and planner
- William Calthorpe (1410-1498), English aristocrat and Knight of the Bath
Other uses:
- Baron Calthorpe, an extinct title in the Peerage of England
- Calthorpe Clinic, an abortion clinic in England