Biosynthesis
Calendic acid is an omega-6 fatty acid. though not usually listed with this group. Calendic acid is synthesised in Calendula officinalis from linoleate by an unusual Δ12-oleate desaturase (a FAD 2 variant) that converts the cis-double bond in position 9 to a trans,trans-conjugated double bond system. An all-trans beta isomer has been described.
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