Ca2+/calmodulin-dependent Protein Kinase
Ca2+/calmodulin-dependent protein kinases II or CaM kinases II are serine/threonine-specific protein kinases that are regulated by the Ca2+/calmodulin complex. CaMKII is involved in many signaling cascades and is thought to be an important mediator of learning and memory. CaMKII is also necessary for Ca2+ homeostasis and reuptake in cardiomyocytes, chloride transport in epithelia, positive T-cell selection, and CD8 T-cell activation.
Misregulation of CaMKII is linked to Alzheimer’s disease, Angelman syndrome, and heart arrhythmia.
Read more about Ca2+/calmodulin-dependent Protein Kinase: Types, Structure, Function, and Autoregulation, Autophosphorylation, Long-Term Potentiation, CaMKII in Behavioral Memory, CaMKII Coding Genes
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