Butanol - Production

Production

Since the 1950s, most butanol in the United States is produced commercially from fossil fuels. The most common process starts with propene (propylene), which is run through a hydroformylation reaction to form butanal, which is then reduced with hydrogen to 1-butanol and/or 2-butanol. Tert-butanol is derived from isobutane as a co-product of propylene oxide production. Butanol can also be produced by fermentation of biomass by bacteria. Prior to the 1950s, Clostridium acetobutylicum was used in industrial fermentation processes producing butanol. Research in the past few decades showed results of other microorganisms that can produce butanol through fermentation.

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