Special Guest Appearances
- Elizabeth Berkley (as Amy; "You Are Me")
- Dan Dierdorf (as himself; "Kick Ball, Get Check")
- Illeana Douglas (as Ginny; "Dating the Teacher")
- Boomer Esiason (as himself; "Kick Ball, Get Check")
- John Michael Higgins (as Mark; "Trick or Treat?", "The Note" and "Politically Impolite")
- Henry Kissinger (as himself; "Politically Impolite")
- Jack Klugman (as Jack; "An Odd Couple of Days")
- Piper Laurie (as Jane Waide; "Everybody Says I Love You")
- Bill Maher (as himself; "Politically Impolite")
- Karl Malone (as himself; "You're in Trouble")
- Al Michaels (as himself; "Kick Ball, Get Check")
- Heather Nauert (as herself; "Politically Impolite")
- Tony Randall (as Tony; "An Odd Couple of Days")
- Bobby Slayton (as himself; "Politically Impolite")
Read more about this topic: Brother's Keeper (TV Series), Cast
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