Brock is a surname, and may refer to
- Andrew C. Brock, Republican member of the North Carolina General Assembly
- Bill Brock (born 1930), Republican United States senator
- C. E. Brock (1870 - 1938), English line artist and illustrator
- Calvin Brock, American boxer
- Darrell Brock Jr., American politician
- Dave Brock, Hawkwind frontman
- David Brock, former conservative journalist turned liberal political writer
- Edwin Brock (1927 - 1997), British poet
- Edwin C. Brock (Egyptologist), American Egyptologist
- Eric John Brock (1966 - 2011), American historian
- Greg Brock (The West Wing), fictional character from The West Wing
- Henry Matthew Brock (1875 - 1960), English illustrator
- Isaac Brock (1769-1812), British major-general
- Isaac Brock (musician) (born 1975), Modest Mouse frontman
- John Brock (baseball), American major league catcher
- John Brock (CEO) (b. 1948), American businessman
- John Brock (fictional character), fictional character of Desmond Skirrow
- John W. Brock (1914-1942), United States Navy officer and Navy Cross recipient
- Juliet Clutton-Brock, British zoologist
- Kathy Brock, American television newsreader
- Lawrence Brock, American politician
- Lillie Brock, elder in the Metropolitan Community Church and LGBT rights activist
- Lou Brock (born 1939), baseball player
- Lou Brock Jr., American football player
- Matthew Brock (disambiguation), multiple people
- Napoleon Murphy Brock, American singer, saxophonist and flautist
- Pete Brock (born 1936), American racing car designer and driver
- Pete Brock (American football), (born 1954) American footballer for the New England Patriots
- Peter Brock (1945 - 2006), Australian motor racing driver
- Raheem Brock, American football player
- Rebecca Wirfs-Brock, author
- Richard Brock, nature film producer
- Robert L. Brock, American anti-Semite
- Russell Brock, Baron Brock, British surgeon who pioneered open heart surgery
- Sebastian Brock, a British Syriacist.
- Stevie Brock (born 1990), American pop singer
- Thomas D. Brock (born 1926), American microbiologist
- Thomas Brock (1847 - 1922), British sculptor
- Tony Brock (born 1954), British drummer
- Tyler Brock, fictional character from Tai-Pan
- William Emerson Brock (1872 – 1950), Democratic United States Senator