Gameplay
Before play begins, the players agree on the number of links necessary to win the game. A game of Brain Chain takes approximately 30 minutes if the goal is four links in a row, an hour if the goal is five links, or 90 minutes if the winning condition is a six-link chain.
Each turn begins with the playing of one movement card and as many Brain Pills as the player wishes and moving the playing pawn, clockwise, the corresponding number of spaces. All players move the same yellow playing pawn. If the pawn does not land on one of the four corner squares, the player then picks a trivia category from the same horizontal row or vertical column as the pawn that is not already occupied by a link. The opposing team will then read a trivia question from the selected category. The player may consult his or her team, but only the player whose turn it is may announce the "final answer." If answered correctly, that player places a link on the chosen square in the category grid and takes a Brain Pill.
If the pawn is moved to one of the four strategic corner squares, instead of picking a category on the row or column the pawn indicates, the player simply follows the instructions on that corner space: Pick any square on the board to answer a question, add a link, remove a link, or move a link.
To create a Brain Chain and win the game a player or team must form an unbroken line of six links in a row vertically, horizontally or diagonally on the Category Grid. The yellow playing pawn is considered a link during a player's turn—allowing a team to win by connecting five links on the border of the grid and moving the pawn to connect with those links.
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