Effects
Such fatigue can become seriously debilitating; in cycling, exhaustion can reach the point where the cyclist is unable to stand without the support provided by the bicycle. Symptoms of depletion include general weakness, fatigue, and manifestations of hypoglycemia, such as dizziness and even hallucinations. This condition will not be relieved by brief periods of rest.
The rising levels of serotonin are caused by increased delivery of tryptophan to the brain. What’s interesting, Davis says, is that the increase in free tryptophan in the blood is very much related to the increase in free fatty acids in the blood. “While many people believe that the increase in free fatty acids is very important to delaying fatigue in the muscle,” says Davis, “we think it has a negative effect in terms of central fatigue.”
To make matters worse for the marathon runner, the brain’s production of dopamine (the neurotransmitter responsible for generating feelings of excitement, reward, motivation, and pleasure) begins to drop even as serotonin levels are rising, which can be the cause of the mental voices in your head telling you "I can't do it" according to Luis Manzo, Ph.D., a sports psychologist and running coach in New York City,which he wrote in Against the wall
Read more about this topic: Bonked
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