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- Blue Meanies (Illinois band), an American ska-core band founded in Carbondale, Illinois
- Blue Meanies (Minneapolis band), Michael Holt, Ricardo Ehramjian, Adrew Platt and Tim Mahoney
- Blue Meanies (Canadian band)
- Blue Meanies (Apple Computer), a former engineering group within Apple Computer
- Blue Meanie, a common name for a type of magic mushroom containing Psilocybin and Psilocin also known as Panaeolus cyanescens
- "The Blue Meanie", real name Brian Heffron, a professional wrestler
- "Blue Meanie", a slang term for police officers
- "Blue Meanies From Outer Space", a game on the VIC20
- "Blue Meanie", a nickname for Holden Dealer Team special edition of the Holden VK Commodore
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