Blondie, Blondy or Blondi may refer to:
- Blondie (band), an American rock band
- Deborah Harry, lead singer of Blondie who is sometimes erroneously referred to by that name
- Blondie (album), the eponymous debut album from Blondie
- Blondie (comic strip), a long-running newspaper comic strip
- Blondie (film) (1938), first in a series of movies based on the comic strip
- Blondie (radio) (1939-1950), a radio comedy series based on the comic strip
- Blondie (1957 TV series), the NBC TV series based on the comic strip
- Blondie (1968 TV series), the updated, short-lived, CBS version
- Blondi, Adolf Hitler's German Shepherd dog
- The nickname of Clint Eastwood's character, the Man with No Name, in the film The Good, the Bad and the Ugly
- Blondie (confection), a brownie made without chocolate
- Someone with exceptionally light blond hair; sometimes this usage is considered offensive