Resistance Genes
Three resistance genes have been cloned:
- bls (an acetyl transferase) from Streptoverticillum sp. which itself produces blasticidin in a natural example of biological warfare
- bsr (a blasticidin-S deaminase) from Bacillus cereus (other bsr genes are known as well, see listings in Genbank)
- BSD (another deaminase) from Aspergillus terreus
bsr and BSD are the most commonly used resistance genes. The proteins produced from these genes enable the cells carrying them to produce protein in the presence of blasticidin.
Read more about this topic: Blasticidin S
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