Biomaterial - Compatibility

Compatibility

Biocompatibility is related to the behavior of biomaterials in various environments under various chemical and physical conditions. The term may refer to specific properties of a material without specifying where or how the material is to be used. For example, a material may elicit little or no immune response in a given organism, and may or may not able to integrate with a particular cell type or tissue). The ambiguity of the term reflects the ongoing development of insights into how biomaterials interact with the human body and eventually how those interactions determine the clinical success of a medical device (such as pacemaker or hip replacement). Modern medical devices and prostheses are often made of more than one material—so it might not always be sufficient to talk about the biocompatibility of a specific material.

Also, a material should not be toxic unless specifically engineered to be so—like "smart" drug delivery systems that target cancer cells and destroy them. Understanding of the anatomy and physiology of the action site is essential for a biomaterial to be effective. An additional factor is the dependence on specific anatomical sites of implantation. It is thus important, during design, to ensure that the implement will fit complementarily and have a beneficial effect with the specific anatomical area of action.

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