Hypothalamic-Pituitary-Adrenal (HPA) Axis
The Hypothalamic-pituitary-adrenal axis is a chain of endocrine structures that are activated during the body's response to stressors of various sorts. It often shows increased activation in depressed people, and drugs that reduce its activity are sometimes effective in reducing symptoms. The HPA influences many parts of the brain, including the Raphe nuclei.
Read more about this topic: Biology Of Depression
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