Other
- Big Spring (Michigan), a spring also called Kitch-iti-kipi, in Palms Book State Park, Schoolcraft County, Michigan
- Big Spring (Missouri), a natural spring (hydrosphere) in the Missouri Ozarks
- Big Spring (Pennsylvania), a historical site in Clearfield County, Pennsylvania
- Big Spring Bombers, a defunct minor league baseball team formerly located in Big Spring, Texas
- Big Spring Cafe, a greasy spoon restaurant located in Huntsville, Alabama
- Big Spring Creek, a tributary of Conodoguinet Creek in Cumberland County, Pennsylvania
- Big Spring Jam, an annual music festival in Huntsville, Alabama
- Big Spring Vietnam Memorial, a war memorial in Big Spring, Texas, honoring American servicemen
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