Big Bill may refer to:
- "Big Bill" Dwyer (1883–1946), prohibition gangster and bootlegger
- "Big Bill" Tilden (1893–1953), American tennis player
- Bill Haywood, (1869–1928), prominent figure of the American labor movement
- Bill James (1887–1942), starting pitcher in Major League Baseball
- Big Bill Bissonnette (born 1937), American jazz trombonist and producer
- Big Bill Broonzy (1898–1958), American blues singer and guitarist
- Big Bill Morganfield (born 1956), American blues singer and guitarist
- Big Bill Neidjie (circa 1920–2002), last surviving speaker of the Gagudju language
- Bill Bachrach (1879-1959), American swim and water polo coach
- Bill Werbeniuk (1947–2003), Canadian snooker player
- Big Bill Laplante (1980- present) Most epic DJ and host of Big Bill's Indie Underground. Calgary Alberta Canada.
Famous quotes containing the words big and/or bill:
“Remembering the Strait of Belle Isle or
some northerly harbor of Labrador,
before he became a schoolteacher
a great-uncle painted a big picture.”
—Elizabeth Bishop (1911–1979)
“It is my belief that there are “absolutes” in our Bill of Rights, and that they were put there on purpose by men who knew what words meant, and meant their prohibitions to be “absolute.””
—Hugo Black (b. 1922)