Bianchini may refer to:
- Bianchini (lunar crater)
- Angela Bianchini (born 1921), Italian fiction writer and literary critic
- Brian Bianchini (1978–2004), American male model
- Francesco Bianchini (1662–1729), Italian philosopher and scientist
- Joseph Bianchini (1704-?), Francesco's nephew, Italian topographer and writer
- Federico Bianchi (painter), Italian painter from the Baroque period
- Federico Bianchi (soccer) (born 1983), American former professional soccer player
- Gina Bianchini, founder of the Ning social networking platform
- Giovanni Bianchini (1410–c. 1449), Italian astronomer
- Giuseppe Bianchini (1704—1764), Italian Oratorian, biblical, historical, and liturgical scholar
- Leslie Bianchini (born 1947), Playboy magazine Playmate of the Month
- Orlando Bianchini (born 1955), Italian hammer thrower
- Vincenzo Bianchini (1903—2000) Italian artist
- Bianchi's planisphere, a planisphere dating back to the 2nd century CE, discovered in Rome in the 18th century