Beta-ketoacyl-acyl-carrier-protein Synthase II

In enzymology, a beta-ketoacyl-acyl-carrier-protein synthase II (EC 2.3.1.179) is an enzyme that catalyzes the chemical reaction

(Z)-hexadec-11-enoyl- + malonyl- (Z)-3-oxooctadec-13-enoyl- + CO₂ +

Thus, the two substrates of this enzyme are ]] and ]], whereas its 3 products are ]], CO₂, and acyl-carrier-protein.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is (Z)-hexadec-11-enoyl-:malonyl- C-acyltransferase (decarboxylating). Other names in common use include KASII, KAS II, FabF, 3-oxoacyl-acyl carrier protein synthase I, and beta-ketoacyl-ACP synthase II. This enzyme participates in fatty acid biosynthesis.