Beta-ketoacyl-acyl-carrier-protein Synthase I

In enzymology, a beta-ketoacyl-acyl-carrier-protein synthase I (EC 2.3.1.41) is an enzyme that catalyzes the chemical reaction

an acyl- + malonyl- a 3-oxoacyl- + CO₂ +

Thus, the two substrates of this enzyme are ]] and ]], whereas its 3 products are ]], CO₂, and acyl carrier protein.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acyl-:malonyl- C-acyltransferase (decarboxylating). Other names in common use include beta-ketoacyl-ACP synthase I, beta-ketoacyl synthetase, beta-ketoacyl-ACP synthetase, beta-ketoacyl-acyl carrier protein synthetase, beta-ketoacyl- synthase, beta-ketoacylsynthase, condensing enzyme, 3-ketoacyl-acyl carrier protein synthase, fatty acid condensing enzyme, acyl-malonyl(acyl-carrier-protein)-condensing enzyme, acyl-malonyl acyl carrier protein-condensing enzyme, beta-ketoacyl acyl carrier protein synthase, 3-oxoacyl- synthase, 3-oxoacyl:ACP synthase I, KASI, KAS I, FabF1, and FabB. This enzyme participates in fatty acid biosynthesis.