Bernice may refer to:
- Berenice or Berenike (Greek: Βερενίκη, Berenikē), a Macedonian name, meaning "bearer of victory" (corresponding to Greek *phere-nikē)
- Berenice (daughter of Herod Agrippa I) is mentioned in the New Testament where her name is spelt "Bernice".
- Place names
- Bernice, California, United States
- Bernice, Louisiana, United States
- Bernice, Oklahoma, United States