Bernadette is a first name, the female form of Bernard. It may refer to:
- St. Bernadette Soubirous, the Marian visionary of Lourdes
- Bernadette Bowyer, Canadian field hockey player
- Bernadette Chirac (born 1933), wife of former French President Jacques Chirac
- Bernadette Lafont (born 1938), French actress
- Bernadette Nolan (born 1960), Irish singer and actress
- Bernadette Devlin McAliskey (born 1947), Irish political activist
- Bernadette Peters, American actress and singer
- Bernadette Rostenkowski, a character on the TV show The Big Bang Theory
- Bernadette Sembrano, Philippino television reporter, newscaster and host
- Bernadette Szőcs (born 1995), Romanian table tennis player
- Bern Nadette Stanis, American actress and writer
- "Bernadette" (song), a 1967 hit recording by the Four Tops
- "Bernadette", a single by IAMX from his 2011 album Volatile Times