Barrera may refer to:
Barrera is a Spanish and Catalan: topographic name for someone who lived near a gate or fence, from Spanish and Catalan barrera ‘barrier’.
- Alejandro Barrera (born 1988), Mexican professional boxer
- Antonio Imbert Barrera (born 1920), Dominican Republic president
- Dagoberto Rodríguez Barrera (born 1955), Cuban diplomat
- Dan Barrera, American mixed martial artist
- Daniel Barrera Barrera, Colombian drug lord
- Elkin Barrera (born 1971), Colombian road cyclist
- Ernesto Barrera, Salvadoran assassinated Roman Catholic priest
- Evaristo Barrera (born 1911), Argentine footballer
- Jesse Barrera (born 1987), American musician, former guitarist of My American Heart
- Jorge Barrera (born 1982), Mexican footballer
- Laz Barrera (1924-1991), American racehorse trainer
- Marco Antonio Barrera (born 1974), Mexican professional boxer
- Melissa Barrera (born 1985), American radio and television personality
- Pablo Barrera (born 1987), Mexican footballer
- Roberto González Barrera, Mexican businessman
- Rodrigo Barrera (born 1970), Chilean footballer
- Roy Barrera, Jr. (born 1952), American lawyer and judge
- Stefano Barrera (born 1980), Italian foil fencer
- Israel S. Barrera (born 1963), American Youth Soccer Coach
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