Baptista is a Portuguese surname. It may refer to:
- Arnaldo Baptista, a Brazilian rock musician
- Baptista Minola, a character in Shakespeare's Taming Of The Shrew play
- Cyro Baptista, a percussionist
- Joseph Baptista, Indian-freedom activist known as Kaka Baptista
- Júlio Baptista, a Brazilian footballer
- Mariano Baptista (1832-1907), President of Bolivia
- Nelsinho Baptista, a former football player and manager
- Vítor Baptista, a Portuguese footballer