Babu may refer to:
- Place
- Babu District, in Hezhou, Guangxi, China
- Title
- Babu (title), South Asian term of respect (meaning 'boss' or 'father')
- People
- Babu (name), list of people with this name
- Babù, Anderson Rodney de Oliveira, Brazilian footballer
- Babu (wrestling), ring name of Pablo Marquez, Ecuadorian wrestler
- DJ Babu, Filipino-American DJ and member of Dilated Peoples
- In media and culture
- Babu (1975 film), a 1975 Telugu film starring Shobhan Babu
- Babu (1985 film), a 1985 Hindi film starring Rajesh Khanna
- Hurree Chunder Mookerjee, character in the Rudyard Kipling novel Kim, mostly referred to as "Hurree Babu" or "the Babu"
- Animals named Babu
- Babu (red panda), red panda that disappeared from a nature centre in Birmingham in 2005